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Dofequidar fumarate
CAS No. 153653-30-6
Dofequidar fumarate ( MS-209 )
产品货号. M12171 CAS No. 153653-30-6
A novel, orally active quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥373 | 有现货 |
|
| 5MG | ￥624 | 有现货 |
|
| 10MG | ￥1029 | 有现货 |
|
| 25MG | ￥2090 | 有现货 |
|
| 50MG | ￥4026 | 有现货 |
|
| 100MG | ￥5856 | 有现货 |
|
| 500MG | ￥12312 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Dofequidar fumarate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A novel, orally active quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR.
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产品描述A novel, orally active quinoline compound that can reverse P-glycoprotein (P-gp)-mediated MDR; completely reverses resistance against vincristine in vitro in multidrug-resistant variants of mouse leukemia P388 cells and human leukemia K562 cells at 1-10 uM; greatly reduces the SP-derived tumor growth in vivo combined with CPT-11.Breast cancer Phase 2 Discontinued
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同义词MS-209
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通路Membrane Transporter/Ion Channel
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靶点P-glycoprotein
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受体P-glycoprotein
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研究领域Cancer
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适应症Breast Cancer
化学信息
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CAS Number153653-30-6
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分子量597.66
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分子式C34H35N3O7
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 56 mg/mL
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SMILESC1CN(CCN1CC(COC2=CC=CC3=C2C=CC=N3)O)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5.C(=CC(=O)O)C(=O)O
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化学全称Ethanone, 1-[4-[2-hydroxy-3-(5-quinolinyloxy)propyl]-1-piperazinyl]-2,2-diphenyl-, (2E)-2-butenedioate (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Nakanishi O, et al. Oncol Res. 1997;9(2):61-9.
2. Sato W, et al. Cancer Chemother Pharmacol. 1995;35(4):271-7.
3. Katayama R, et al. Cancer Sci. 2009 Nov;100(11):2060-8.
2. Sato W, et al. Cancer Chemother Pharmacol. 1995;35(4):271-7.
3. Katayama R, et al. Cancer Sci. 2009 Nov;100(11):2060-8.
产品手册
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